New publication of COSM group : “Relevance of Palladium to Radiopharmaceutical Development Considering Enhanced Coordination Properties of TE1PA”
Julie Pineau, Luís M. P. Lima, Carlos Platas-Iglesias, Jan Rijn Zeevaart, Cathryn H. S. Driver, Nathalie Le Bris, Raphaël Tripier
Since the macrocyclic gold standards used in nuclear medicine are not suitable to Pd(II) coordination, its radioisotopes remain understated for radiopharmaceutical applications. The monopicolinate cyclam TE1PA presented here is a highly relevant chelator for natural and radioactive Pd, opening avenues to enrich the current palette of radiopharmaceuticals for targeted radiotherapy.